I have all the latest updates installed for hardware and software. The first time i ran the game i had all the video settings set high and checked. It was ran fine until dawn then it started to get real choppy and sluggish. I turned off anti-alias and it helped a little. I turned off vertical-sync and saw no improvement. I finally lowered my detail level to medium as well as shadows; currents settings. So far, the game seems to be running smooth but still has a problem with entering caves and such where i get choppy or pausing. The symptons i experienced during the game were all during hosting local multiplayer games. I played the first 8 hours by myself but then add another player the cave choppyness increases for me as well as for the other player. I have three copies of the game, one for everyone playing, and we all are experiencing similar or the same issues.
--Not sure if this is suppose to be true but ensnare for hunter is doing damage over time without having the barbed nettting skill. I see creatures in the game using the skill and having the same effect on me.
--Not being able to rotate camera around the character gets frustrating when creatures are coming at you from the bootom of the screen. I often press buttons by accident on the UI trying to attack.
--Not being able to assign keys for movement. Im getting tired of of the constant clicking or having to hold it down to move around. My wrists are getting sore.
--Not being able to adjust the camera angle gets frustrating in some tight spots.
So far im stuck on the road to Athens. Somehow my character got bugged and no matter how many times i kill the three medusas i still cant get beyond the gate. I had to start a new character.
Thats my experience so far and if i have anymore to add i will edit the post. I really like the game because its like having the hack&slash fun of DiabloII with the spacious zones like dungeon siege. The skill tree is by far the most attractive part of the game for me.